About Protein FAM177A1
Protein FAM177A1 (FAM177A1) is a protein
from Homo sapiens identified by UniProt accession
Q8N128, 213 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Protein FAM177A1 |
|---|
| UniProt accession | Q8N128 |
|---|
| Gene | FAM177A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 213 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.28
- leukocyte count · score 0.28
- Intellectual disability · score 0.26
- Dolichocephaly · score 0.26
- Macrocephaly · score 0.26
- obesity · score 0.26
- monocyte count · score 0.24
- blood protein measurement · score 0.23
- lymphocyte count · score 0.21
- monocyte percentage of leukocytes · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N128-F1 | alphafold | PREDICTED | 63.43 | — |
Amino-acid sequence (213 residues)
MDQEPVGGVE RGEAVAASGA AAAAAFGESA GQMSNERGFE NVELGVIGKK KKVPRRVIHF VSGETMEEYS TDEDEVDGLE KKDVLPTVDP TKLTWGPYLW FYMLRAATST LSVCDFLGEK IASVLGISTP KYQYAIDEYY RMKKEEEEEE EENRMSEEAE KQYQQNKLQT DSIVQTDQPE TVISSSFVNV NFEMEGDSEV IMESKQNPVS VPP
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