About Porimin
Porimin (TMEM123) is a protein
from Homo sapiens identified by UniProt accession
Q8N131, 208 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Porimin |
|---|
| UniProt accession | Q8N131 |
|---|
| Gene | TMEM123 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- cancer · score 0.08
- neoplasm · score 0.06
- metabolite measurement · score 0.04
- reticulocyte count · score 0.03
- neutrophil count · score 0.03
- alkaline phosphatase measurement · score 0.03
- Cleft palate · score 0.02
- leukocyte count · score 0.02
- diastolic blood pressure · score 0.02
- non-small cell lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N131-F1 | alphafold | PREDICTED | 59.56 | — |
Amino-acid sequence (208 residues)
MGLGARGAWA ALLLGTLQVL ALLGAAHESA AMAASANIEN SGLPHNSSAN STETLQHVPS DHTNETSNST VKPPTSVASD SSNTTVTTMK PTAASNTTTP GMVSTNMTST TLKSTPKTTS VSQNTSQIST STMTVTHNSS VTSAASSVTI TTTMHSEAKK GSKFDTGSFV GGIVLTLGVL SILYIGCKMY YSRRGIRYRT IDEHDAII
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