EP300-interacting inhibitor of differentiation 3 (EID3)

Homo sapiens — UniProt Q8N140

Gene: EID3Homo sapiensSwissProt reviewed

About EP300-interacting inhibitor of differentiation 3

EP300-interacting inhibitor of differentiation 3 (EID3) is a protein from Homo sapiens identified by UniProt accession Q8N140, 333 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein nameEP300-interacting inhibitor of differentiation 3
UniProt accessionQ8N140
GeneEID3
OrganismHomo sapiens
Length333 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • breast adenocarcinoma · score 0.23
  • esophageal cancer · score 0.14
  • genetic disorder · score 0.12
  • cancer · score 0.02
  • infection · score 0.01
  • infect · score 0.01
  • glioblastoma multiforme · score 0.01
  • hepatocellular carcinoma · score 0.01
  • neoplasm · score 0.01
  • IGA glomerulonephritis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N140-F1alphafoldPREDICTED72.98—

Amino-acid sequence (333 residues)

MKMDVSVRAA GCSDDLSSGE ADVDPKLLEL TADEEKCRSI RRQYRQLMYC VRQNREDIVS SANNSLTEAL EEANVLFDGV SRTREAALDA RFLVMASDLG KEKAKQLNSD MNFFNQLAFC DFLFLFVGLN WMEGDPDKLS DCDDSIALSF WKAIEKEATS WMVKAETFHF VFGSFKLERS APKPRLEHQK KVRKMEENGN MPTKLQKLDL SSYPEATEKN VERILGLLQT YFRKYPDTPV SYFEFVIDPN SFSRTVENIF YVSFIVRDGF ARIRLDEDRL PILEPMNVNQ MGEGNDSSCH GRKQGVISLT LQEWKNIVAA FEISEAMITY SSY

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Quick facts

UniProtQ8N140
GeneEID3
OrganismHomo sapiens
Length333
Binders0
Diseases15
View on UniProt