About Leukocyte immunoglobulin-like receptor subfamily A member 2
Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2) is a protein
from Homo sapiens identified by UniProt accession
Q8N149, 483 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 2 |
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| UniProt accession | Q8N149 |
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| Gene | LILRA2 |
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| Organism | Homo sapiens |
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| Length | 483 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (36)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.24
- protein measurement · score 0.11
- microscopic polyangiitis · score 0.03
- Systemic lupus erythematosus · score 0.03
- Crohn's disease · score 0.02
- HIV infection · score 0.02
- ulcerative colitis · score 0.02
- cancer · score 0.01
- neoplasm · score 0.01
- osteosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N149-F1 | alphafold | PREDICTED | 86.06 | — |
Amino-acid sequence (483 residues)
MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVII QGSPVTLRCQ GSLQAEEYHL YRENKSASWV RRIQEPGKNG QFPIPSITWE HAGRYHCQYY SHNHSSEYSD PLELVVTGAY SKPTLSALPS PVVTSGGNVT LQCVSQVAFD GFILCKEGED EHPQRLNSHS HARGWSWAIF SVGPVSPSRR WSYRCYAYDS NSPYVWSLPS DLLELLVPGV SKKPSLSVQP GPMVAPGESL TLQCVSDVGY DRFVLYKEGE RDFLQRPGWQ PQAGLSQANF TLGPVSPSHG GQYRCYSAHN LSSEWSAPSD PLDILITGQF YDRPSLSVQP VPTVAPGKNV TLLCQSRGQF HTFLLTKEGA GHPPLHLRSE HQAQQNQAEF RMGPVTSAHV GTYRCYSSLS SNPYLLSLPS DPLELVVSEA AETLSPSQNK TDSTTTSLGQ HPQDYTVENL IRMGVAGLVL VVLGILLFEA QHSQRSLQDA AGR
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