Serine/threonine-protein kinase PDIK1L (PDIK1L)

About Serine/threonine-protein kinase PDIK1L

Serine/threonine-protein kinase PDIK1L (PDIK1L) is a protein from Homo sapiens identified by UniProt accession Q8N165, 341 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.

Target properties

Protein name	Serine/threonine-protein kinase PDIK1L
UniProt accession	Q8N165
Gene	PDIK1L
Organism	Homo sapiens
Length	341 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (90)

Diseases linked to this target (Open Targets).

body height · score 0.30
neurodegenerative disease · score 0.29
IGF-1 measurement · score 0.27
lean body mass · score 0.27
forced expiratory volume · score 0.26
appendicular lean mass · score 0.22
fat body mass · score 0.21
vital capacity · score 0.20
sitting height measurement · score 0.20
electrocardiography · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N165-F1	alphafold	PREDICTED	85.73	—

Amino-acid sequence (341 residues)

MVSSQPKYDL IREVGRGSYG VVYEAVIRKT SARVAVKKIR CHAPENVELA LREFWALSSI KSQHPNVIHL EECILQKDGM VQKMSHGSNS SLYLQLVETS LKGEIAFDPR SAYYLWFVMD FCDGGDMNEY LLSRKPNRKT NTSFMLQLSS ALAFLHKNQI IHRDLKPDNI LISQTRLDTS DLEPTLKVAD FGLSKVCSAS GQNPEEPVSV NKCFLSTACG TDFYMAPEVW EGHYTAKADI FALGIIIWAM LERITFIDTE TKKELLGSYV KQGTEIVPVG EALLENPKME LLIPVKKKSM NGRMKQLIKE MLAANPQDRP DAFELELRLV QIAFKDSSWE T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards