Histone H2B type 3-B (H2BC26)

About Histone H2B type 3-B

Histone H2B type 3-B (H2BC26) is a protein from Homo sapiens identified by UniProt accession Q8N257, 126 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Histone H2B type 3-B
UniProt accession	Q8N257
Gene	H2BC26
Organism	Homo sapiens
Length	126 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

infectious disease · score 0.50
viral disease · score 0.50
breast carcinoma · score 0.38
cancer · score 0.37
melanoma · score 0.37
burn · score 0.02
metastatic melanoma · score 0.01
lung adenocarcinoma · score 0.01
COVID-19 · score 0.01
Systemic lupus erythematosus · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N257-F1	alphafold	PREDICTED	87.55	—

Amino-acid sequence (126 residues)

MPDPSKSAPA PKKGSKKAVT KAQKKDGKKR KRGRKESYSI YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIASEASR LAHYNKRSTI TSREVQTAVR LLLPGELAKH AVSEGTKAVT KYTSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards