Protein GAPT (GAPT)

About Protein GAPT

Protein GAPT (GAPT) is a protein from Homo sapiens identified by UniProt accession Q8N292, 157 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.

Target properties

Protein name	Protein GAPT
UniProt accession	Q8N292
Gene	GAPT
Organism	Homo sapiens
Length	157 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (137)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.32
mathematical ability · score 0.23
lymphocyte count · score 0.23
triglyceride measurement · score 0.21
leukocyte count · score 0.18
monocyte count · score 0.17
intelligence · score 0.17
neutrophil count · score 0.17
myeloid white cell count · score 0.17
adolescent idiopathic scoliosis · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N292-F1	alphafold	PREDICTED	63.25	—

Amino-acid sequence (157 residues)

MSKSCGNNLA AISVGISLLL LLVVCGIGCV WHWKHRVATR FTLPRFLQRR SSRRKVCTKT FLGPRIIGLR HEISVETQDH KSAVRGNNTH DNYENVEAGP PKAKGKTDKE LYENTGQSNF EEHIYGNETS SDYYNFQKPR PSEVPQDEDI YILPDSY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards