Armadillo repeat-containing protein 10 (ARMC10)

About Armadillo repeat-containing protein 10

Armadillo repeat-containing protein 10 (ARMC10) is a protein from Homo sapiens identified by UniProt accession Q8N2F6, 343 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Armadillo repeat-containing protein 10
UniProt accession	Q8N2F6
Gene	ARMC10
Organism	Homo sapiens
Length	343 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.09
pancreatic adenocarcinoma · score 0.08
neoplasm · score 0.03
lower face morphology measurement · score 0.03
Ischemic stroke · score 0.01
nervous system disease · score 0.01
hepatocellular carcinoma · score 0.01
Intestinal epithelial dysplasia · score 0.01
cancer · score 0.01
melanoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N2F6-F1	alphafold	PREDICTED	80.20	—

Amino-acid sequence (343 residues)

MGGPRGAGWV AAGLLLGAGA CYCIYRLTRG RRRGDRELGI RSSKSAGALE EGTSEGQLCG RSARPQTGGT WESQWSKTSQ PEDLTDGSYD DVLNAEQLQK LLYLLESTED PVIIERALIT LGNNAAFSVN QAIIRELGGI PIVANKINHS NQSIKEKALN ALNNLSVNVE NQIKIKIYIS QVCEDVFSGP LNSAVQLAGL TLLTNMTVTN DHQHMLHSYI TDLFQVLLTG NGNTKVQVLK LLLNLSENPA MTEGLLRAQV DSSFLSLYDS HVAKEILLRV LTLFQNIKNC LKIEGHLAVQ PTFTEGSLFF LLHGEECAQK IRALVDHHDA EVKEKVVTII PKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards