Protein FAM43A (FAM43A)

About Protein FAM43A

Protein FAM43A (FAM43A) is a protein from Homo sapiens identified by UniProt accession Q8N2R8, 423 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	Protein FAM43A
UniProt accession	Q8N2R8
Gene	FAM43A
Organism	Homo sapiens
Length	423 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (51)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.39
hematocrit · score 0.39
reticulocyte count · score 0.38
neutrophil count · score 0.37
hemoglobin measurement · score 0.37
eosinophil percentage of leukocytes · score 0.37
erythrocyte count · score 0.36
reticulocyte measurement · score 0.35
cortical thickness · score 0.34
red blood cell density measurement · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N2R8-F1	alphafold	PREDICTED	62.87	—

Amino-acid sequence (423 residues)

MLPWKKHKFE LLAEAPPRQA SKPKGYAVSL HYSALSSLAR ACPEGALSRV GSMFRSKRKK LHITSEDPTY TVLYLGNATT IQARGDGCTD LAVGKIWSKS EAGRQGTKMK LTVSAQGIRM VHAEERALRR PGHLYLLHRV TYCVADARLP KVFAWVYRHE LKHKAVMLRC HAVLVSKPEK AQAMALLLYQ TSANALAEFK RLKRRDDARH QQQELVGAHT IPLVPLRKLL LHGPCCYKPP VERSRSAPKL GSITEDLLGE QLEQELQEEE EEEQPEGCPE EEENRAAEGD PAEEEAEAQR ALVVAMHFEC GDLLDTLENG RGEALGGGGG SLGPGAGPPP LLLGSASDMK AELSQLISDL GELSFGNDVR TLQADLRVTR LLSGDSTGSE SSIEGGGPDA TSATAGDSSR QADGASADEP HSG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards