About Angiogenic factor with G patch and FHA domains 1
Angiogenic factor with G patch and FHA domains 1 (AGGF1) is a protein
from Homo sapiens identified by UniProt accession
Q8N302, 714 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | Angiogenic factor with G patch and FHA domains 1 |
|---|
| UniProt accession | Q8N302 |
|---|
| Gene | AGGF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 714 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (109)
Diseases linked to this target (Open Targets).
- cancer · score 0.55
- neurodegenerative disease · score 0.27
- non-syndromic syndactyly · score 0.27
- thyroid gland adenocarcinoma · score 0.26
- lung adenocarcinoma · score 0.23
- breast adenocarcinoma · score 0.18
- Varicose veins · score 0.14
- hepatocellular carcinoma · score 0.10
- endometrial cancer · score 0.09
- subarachnoid hemorrhage · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N302-F1 | alphafold | PREDICTED | 65.74 | — |
Amino-acid sequence (714 residues)
MASEAPSPPR SPPPPTSPEP ELAQLRRKVE KLERELRSCK RQVREIEKLL HHTERLYQNA ESNNQELRTQ VEELSKILQR GRNEDNKKSD VEVQTENHAP WSISDYFYQT YYNDVSLPNK VTELSDQQDQ AIETSILNSK DHLQVENDAY PGTDRTENVK YRQVDHFASN SQEPASALAT EDTSLEGSSL AESLRAAAEA AVSQTGFSYD ENTGLYFDHS TGFYYDSENQ LYYDPSTGIY YYCDVESGRY QFHSRVDLQP YPTSSTKQSK DKKLKKKRKD PDSSATNEEK DLNSEDQKAF SVEHTSCNEE ENFANMKKKA KIGIHHKNSP PKVTVPTSGN TIESPLHENI SNSTSFKDEK IMETDSEPEE GEITDSQTED SYDEAITSEG NVTAEDSEDE DEDKIWPPCI RVIVIRSPVL QIGSLFIITA VNPATIGREK DMEHTLRIPE VGVSKFHAEI YFDHDLQSYV LVDQGSQNGT IVNGKQILQP KTKCDPYVLE HGDEVKIGET VLSFHIHPGS DTCDGCEPGQ VRAHLRLDKK DESFVGPTLS KEEKELERRK ELKKIRVKYG LQNTEYEDEK TLKNPKYKDR AGKRREQVGS EGTFQRDDAP ASVHSEITDS NKGRKMLEKM GWKKGEGLGK DGGGMKTPIQ LQLRRTHAGL GTGKPSSFED VHLLQNKNKK NWDKARERFT ENFPETKPQK DDPGTMPWVK GTLE
Explore Angiogenic factor with G patch and FHA domains 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets