About Solute carrier family 35 member F6
Solute carrier family 35 member F6 (SLC35F6) is a protein
from Homo sapiens identified by UniProt accession
Q8N357, 371 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Solute carrier family 35 member F6 |
|---|
| UniProt accession | Q8N357 |
|---|
| Gene | SLC35F6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 371 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- body mass index · score 0.15
- lean body mass · score 0.14
- body fat percentage · score 0.13
- fat body mass · score 0.13
- age at first sexual intercourse measurement · score 0.12
- waist circumference · score 0.09
- body height · score 0.08
- aspartate aminotransferase measurement · score 0.08
- sex hormone-binding globulin measurement · score 0.08
- high density lipoprotein cholesterol measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N357-F1 | alphafold | PREDICTED | 84.30 | — |
Amino-acid sequence (371 residues)
MAWTKYQLFL AGLMLVTGSI NTLSAKWADN FMAEGCGGSK EHSFQHPFLQ AVGMFLGEFS CLAAFYLLRC RAAGQSDSSV DPQQPFNPLL FLPPALCDMT GTSLMYVALN MTSASSFQML RGAVIIFTGL FSVAFLGRRL VLSQWLGILA TIAGLVVVGL ADLLSKHDSQ HKLSEVITGD LLIIMAQIIV AIQMVLEEKF VYKHNVHPLR AVGTEGLFGF VILSLLLVPM YYIPAGSFSG NPRGTLEDAL DAFCQVGQQP LIAVALLGNI SSIAFFNFAG ISVTKELSAT TRMVLDSLRT VVIWALSLAL GWEAFHALQI LGFLILLIGT ALYNGLHRPL LGRLSRGRPL AEESEQERLL GGTRTPINDA S
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