About Mucin-15
Mucin-15 (MUC15) is a protein
from Homo sapiens identified by UniProt accession
Q8N387, 334 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Mucin-15 |
|---|
| UniProt accession | Q8N387 |
|---|
| Gene | MUC15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 334 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.27
- squamous cell lung carcinoma · score 0.27
- breast adenocarcinoma · score 0.26
- endometrial cancer · score 0.25
- head and neck squamous cell carcinoma · score 0.22
- gastric adenocarcinoma · score 0.17
- dystonic disorder · score 0.15
- Dystonia · score 0.15
- genetic disorder · score 0.12
- multiple myeloma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N387-F1 | alphafold | PREDICTED | 52.23 | — |
Amino-acid sequence (334 residues)
MLALAKILLI STLFYSLLSG SHGKENQDIN TTQNIAEVFK TMENKPISLE SEANLNSDKE NITTSNLKAS HSPPLNLPNN SHGITDFSSN SSAEHSLGSL KPTSTISTSP PLIHSFVSKV PWNAPIADED LLPISAHPNA TPALSSENFT WSLVNDTVKT PDNSSITVSI LSSEPTSPSV TPLIVEPSGW LTTNSDSFTG FTPYQEKTTL QPTLKFTNNS KLFPNTSDPQ KENRNTGIVF GAILGAILGV SLLTLVGYLL CGKRKTDSFS HRRLYDDRNE PVLRLDNAPE PYDVSFGNSS YYNPTLNDSA MPESEENARD GIPMDDIPPL RTSV
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