About Zinc finger protein 786
Zinc finger protein 786 (ZNF786) is a protein
from Homo sapiens identified by UniProt accession
Q8N393, 782 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Zinc finger protein 786 |
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| UniProt accession | Q8N393 |
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| Gene | ZNF786 |
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| Organism | Homo sapiens |
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| Length | 782 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (25)
Diseases linked to this target (Open Targets).
- basophil percentage of leukocytes · score 0.25
- neutrophil count · score 0.23
- sum of neutrophil and eosinophil counts · score 0.19
- sum of basophil and neutrophil counts · score 0.18
- myeloid white cell count · score 0.12
- leukocyte count · score 0.11
- neutrophil percentage of leukocytes · score 0.10
- neuroimaging measurement · score 0.08
- brain volume measurement · score 0.08
- monocyte percentage of leukocytes · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N393-F1 | alphafold | PREDICTED | 63.01 | — |
Amino-acid sequence (782 residues)
MAEPPRLPLT FEDVAIYFSE QEWQDLEAWQ KELYKHVMRS NYETLVSLDD GLPKPELISW IEHGGEPFRK WRESQKSGNI ICSSVDMHFD PGFEEQLFWG SQQAMNSGKT KSHFQLDPES QCSFGSFVSF RPDQGITLGS PQRHDARAPP PLACGPSEST LKEGIPGPRN LDLPGLWDVP AWESTQHPWP VCGESCWENN HLVMHQRGHS KDRTRRAWEK FNKRAETQMP WSSPRVQRHF RCGVCGKSFR RKLCLLRHLA AHTGRGPFRN ADGEMCFRHE LTHPSHRLPQ QGEKPAQCTP CGKRSLPVDS TQARRCQHSR EGPASWREGR GASSSVHSGQ KPGSRLPQEG NSHQEGDTEA LQHGAEGPCS CSECGERSPM SARLASPCRA HTGEKPFQCA HCTKRFRLRR LLQVHQHAHG GERPFSCRKC GKGFAKQCKL TEHIRVHSGE KPFRCAKCGR NFRQRGQLLR HQRLHTDEKP FQCPECGLSF RLESMLRAHR LRHGGERPFS CSECGRGFTH QCKLREHLRV HSGERPFQCL KCDKRFRLKG ILKAHQHTHS KERPFSCGEC GKGFTRQSKL TEHLRVHSGE RPFQCPECNR SFRLKGQLLS HQRLHTGERP FQCPECDKRY RVKADMKAHQ LLHSGEMPFS CECGKGFVKH SKLIEHIRTH TGEKPFQCPK CDKSFRLKAQ LLSHQGLHTG ERPFHCPECD KNFRERGHML RHQRIHRPER PFACGDCGKG FIYKSKLAEH IRVHTKSCPA PNELDIKKRL SQLFAMIEAD WS
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