About MICAL-like protein 1
MICAL-like protein 1 (MICALL1) is a protein
from Homo sapiens identified by UniProt accession
Q8N3F8, 863 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | MICAL-like protein 1 |
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| UniProt accession | Q8N3F8 |
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| Gene | MICALL1 |
|---|
| Organism | Homo sapiens |
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| Length | 863 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- platelet component distribution width · score 0.32
- body mass index · score 0.19
- platelet count · score 0.15
- heel bone mineral density · score 0.13
- bone quantitative ultrasound measurement · score 0.12
- mean platelet volume · score 0.06
- refractive error measurement · score 0.05
- smoking behavior · score 0.04
- smoking status measurement · score 0.04
- erythrocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N3F8-F1 | alphafold | PREDICTED | 57.87 | — |
Amino-acid sequence (863 residues)
MAGPRGALLA WCRRQCEGYR GVEIRDLSSS FRDGLAFCAI LHRHRPDLLD FDSLSKDNVF ENNRLAFEVA EKELGIPALL DPNDMVSMSV PDCLSIMTYV SQYYNHFCSP GQAGVSPPRK GLAPCSPPSV APTPVEPEDV AQGEELSSGS LSEQGTGQTP SSTCAACQQH VHLVQRYLAD GRLYHRHCFR CRRCSSTLLP GAYENGPEEG TFVCAEHCAR LGPGTRSGTR PGPFSQPKQQ HQQQLAEDAK DVPGGGPSSS APAGAEADGP KASPEARPQI PTKPRVPGKL QELASPPAGR PTPAPRKASE STTPAPPTPR PRSSLQQENL VEQAGSSSLV NGRLHELPVP KPRGTPKPSE GTPAPRKDPP WITLVQAEPK KKPAPLPPSS SPGPPSQDSR QVENGGTEEV AQPSPTASLE SKPYNPFEEE EEDKEEEAPA APSLATSPAL GHPESTPKSL HPWYGITPTS SPKTKKRPAP RAPSASPLAL HASRLSHSEP PSATPSPALS VESLSSESAS QTAGAELLEP PAVPKSSSEP AVHAPGTPGN PVSLSTNSSL ASSGELVEPR VEQMPQASPG LAPRTRGSSG PQPAKPCSGA TPTPLLLVGD RSPVPSPGSS SPQLQVKSSC KENPFNRKPS PAASPATKKA TKGSKPVRPP APGHGFPLIK RKVQADQYIP EEDIHGEMDT IERRLDALEH RGVLLEEKLR GGLNEGREDD MLVDWFKLIH EKHLLVRRES ELIYVFKQQN LEQRQADVEY ELRCLLNKPE KDWTEEDRAR EKVLMQELVT LIEQRNAIIN CLDEDRQREE EEDKMLEAMI KKKEFQREAE PEGKKKGKFK TMKMLKLLGN KRDAKSKSPR DKS
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