Fibroblast growth factor receptor-like 1 (FGFRL1)

Homo sapiens — UniProt Q8N441

Gene: FGFRL1Homo sapiensSwissProt reviewed

About Fibroblast growth factor receptor-like 1

Fibroblast growth factor receptor-like 1 (FGFRL1) is a protein from Homo sapiens identified by UniProt accession Q8N441, 504 residues long. MolForge cross-references it against 0 known binders and 118 disease associations.

Target properties

Protein nameFibroblast growth factor receptor-like 1
UniProt accessionQ8N441
GeneFGFRL1
OrganismHomo sapiens
Length504 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N441-F1alphafoldPREDICTED71.25—

Amino-acid sequence (504 residues)

MTPSPLLLLL LPPLLLGAFP PAAAARGPPK MADKVVPRQV ARLGRTVRLQ CPVEGDPPPL TMWTKDGRTI HSGWSRFRVL PQGLKVKQVE REDAGVYVCK ATNGFGSLSV NYTLVVLDDI SPGKESLGPD SSSGGQEDPA SQQWARPRFT QPSKMRRRVI ARPVGSSVRL KCVASGHPRP DITWMKDDQA LTRPEAAEPR KKKWTLSLKN LRPEDSGKYT CRVSNRAGAI NATYKVDVIQ RTRSKPVLTG THPVNTTVDF GGTTSFQCKV RSDVKPVIQW LKRVEYGAEG RHNSTIDVGG QKFVVLPTGD VWSRPDGSYL NKLLITRARQ DDAGMYICLG ANTMGYSFRS AFLTVLPDPK PPGPPVASSS SATSLPWPVV IGIPAGAVFI LGTLLLWLCQ AQKKPCTPAP APPLPGHRPP GTARDRSGDK DLPSLAALSA GPGVGLCEEH GSPAAPQHLL GPGPVAGPKL YPKLYTDIHT HTHTHSHTHS HVEGKVHQHI HYQC

Explore Fibroblast growth factor receptor-like 1 with MolForge

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Quick facts

UniProtQ8N441
GeneFGFRL1
OrganismHomo sapiens
Length504
Binders0
Diseases118
View on UniProt