RIB43A-like with coiled-coils protein 1 (RIBC1)

About RIB43A-like with coiled-coils protein 1

RIB43A-like with coiled-coils protein 1 (RIBC1) is a protein from Homo sapiens identified by UniProt accession Q8N443, 379 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	RIB43A-like with coiled-coils protein 1
UniProt accession	Q8N443
Gene	RIBC1
Organism	Homo sapiens
Length	379 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

ependymoma · score 0.02
autism · score 0.01
myelodysplastic syndrome · score 0.00
chronic rhinosinusitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N443-F1	alphafold	PREDICTED	83.78	—

Amino-acid sequence (379 residues)

MYNIKQSTDT KEAAAIEARR NREKERQNRF FNVRNRVMGV DVQALNNQVG DRKRREAAER SKEAAYGTSQ VQYDVVVQML EKEEADRTRQ LAKKVQEFRE QKQQLKNGRE FSLWDPGQVW KGLPTYLSYS NTYPGPASLQ YFSGEDLDRD TRLRMQQGQF RYNLERQQQE QQQAKVDENY TDALSNQLRL AMDAQATHLA RLEESCRAAM MCAMANANKA QAAVQAGRQR CERQREQKAN LAEIQHQSTS DLLTENPQVA QHPMAPYRVL PYCWKGMTPE QQAAIRKEQE VQRSKKQAHR QAEKTLDTEW KSQTMSSAQA VLELEEQERE LCAVFQRGLG SFNQQLANEQ KAQQDYLNSV IYTNQPTAQY HQQFNTSSR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards