Zinc finger protein 843 (ZNF843)

About Zinc finger protein 843

Zinc finger protein 843 (ZNF843) is a protein from Homo sapiens identified by UniProt accession Q8N446, 348 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 843
UniProt accession	Q8N446
Gene	ZNF843
Organism	Homo sapiens
Length	348 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.29
neuroinflammatory disorder · score 0.24
mean corpuscular hemoglobin · score 0.07
Glycosuria · score 0.06
platelet count · score 0.05
gestational blood glucose measurement · score 0.04
parental genotype effect measurement · score 0.04
mean corpuscular volume · score 0.03
Red cell distribution width · score 0.03
osteosarcoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N446-F1	alphafold	PREDICTED	46.96	—

Amino-acid sequence (348 residues)

MRSLPFALTV ESVSARAPTC CSTGRFTQGR QPCKCKACGR GFTQSASLLQ HWRVHSDWRE TLSLSPVRQD LLWPLQPHQA PASPLGRSHS SAGVRQGFSG QLCCWLTKEH TLAEALRLSP VPAGFWGPVE ADRPPANSHR RVCPFCCCSC GDSVNEKTSL SQRVLPHPGE KTCRGGSVES VSLAPSSVAP DSTSGLRPCG SPGSFLQHLP PSTLLPRPPF LYPGPPLSLQ PLVPSGLPAV PAVPLGGLEV AQVPPATQPA AQQEGAMGPR SCASAGRDSR EAVQAPGYPE PARKASQHRA AGPLGEARAR LQRQCRAPPP PSNPHWRGAL PVFPVWKASS RRSNLARH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards