Solute carrier family 60 member 1 (SLC60A1)

About Solute carrier family 60 member 1

Solute carrier family 60 member 1 (SLC60A1) is a protein from Homo sapiens identified by UniProt accession Q8N468, 514 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Solute carrier family 60 member 1
UniProt accession	Q8N468
Gene	SLC60A1
Organism	Homo sapiens
Length	514 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

glomerular filtration rate · score 0.24
leukocyte count · score 0.21
creatinine measurement · score 0.19
papillary thyroid carcinoma · score 0.07
neoplasm · score 0.04
clear cell renal carcinoma · score 0.04
gastric carcinoma · score 0.04
glioblastoma multiforme · score 0.04
astrocytoma · score 0.04
gonorrhea · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N468-F1	alphafold	PREDICTED	77.20	—

Amino-acid sequence (514 residues)

MGCDGRVSGL LRRNLQPTLT YWSVFFSFGL CIAFLGPTLL DLRCQTHSSL PQISWVFFSQ QLCLLLGSAL GGVFKRTLAQ SLWALFTSSL AISLVFAVIP FCRDVKVLAS VMALAGLAMG CIDTVANMQL VRMYQKDSAV FLQVLHFFVG FGALLSPLIA DPFLSEANCL PANSTANTTS RGHLFHVSRV LGQHHVDAKP WSNQTFPGLT PKDGAGTRVS YAFWIMALIN LPVPMAVLML LSKERLLTCC PQRRPLLLSA DELALETQPP EKEDASSLPP KFQSHLGHED LFSCCQRKNL RGAPYSFFAI HITGALVLFM TDGLTGAYSA FVYSYAVEKP LSVGHKVAGY LPSLFWGFIT LGRLLSIPIS SRMKPATMVF INVVGVVVTF LVLLIFSYNV VFLFVGTASL GLFLSSTFPS MLAYTEDSLQ YKGCATTVLV TGAGVGEMVL QMLVGSIFQA QGSYSFLVCG VIFGCLAFTF YILLLFFHRM HPGLPSVPTQ DRSIGMENSE CYQR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards