About Steroid transmembrane transporter SLC22A24
Steroid transmembrane transporter SLC22A24 (SLC22A24) is a protein
from Homo sapiens identified by UniProt accession
Q8N4F4, 552 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Steroid transmembrane transporter SLC22A24 |
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| UniProt accession | Q8N4F4 |
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| Gene | SLC22A24 |
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| Organism | Homo sapiens |
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| Length | 552 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.38
- urinary metabolite measurement · score 0.31
- serum metabolite measurement · score 0.24
- eye injury · score 0.10
- progesterone measurement · score 0.03
- hormone measurement · score 0.03
- COVID-19 · score 0.03
- neoplasm · score 0.01
- adrenal cortex carcinoma · score 0.01
- acne · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N4F4-F1 | alphafold | PREDICTED | 87.71 | — |
Amino-acid sequence (552 residues)
MGFDVLLDQV GGMGRFQICL IAFFCITNIL LFPNIVLENF TAFTPSHRCW VPLLDNDTVS DNDTGTLSKD DLLRISIPLD SNLRPQKCQR FIHPQWQLLH LNGTFPNTNE PDTEPCVDGW VYDRSSFLST IVTEWDLVCE SQSLKSMVQS LFMAGSLLGG LIYGHLSDRV GRKIICKLCF LQLAISNTCA AFAPTFLVYC ILRFLAGFST MTILGNTFIL SLEWTLPRSR SMTIMVLLCS YSVGQMLLGG LAFAIQDWHI LQLTVSTPII VLFLSSWKMV ESARWLIINN QLDEGLKELR RVAHINGKKN TEETLTTELV RSTMKKELDA VRIKTSIFSL FRAPKLRMRV FGLCFVRFAI TVPFYGLILN LQHLGSNVSL FQILCGAVTF TARCVSLLTL NHMGRRISQI LFTFPVGLFI LVNTFLPQEM QILRVVLATL GIGSVSAASN SASVHHNELV PTILRSTVAG INAVSGRTGA ALAPLLMTLM AYSPHLPWIS YGVFPILAVP VILLLPETRD LPLPNTIQDV ENDRKDSRNI KQEDTCMKVT QF
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