Vacuolar ATPase assembly protein VMA12 (VMA12)

Homo sapiens — UniProt Q8N511

Gene: VMA12Homo sapiensSwissProt reviewed

About Vacuolar ATPase assembly protein VMA12

Vacuolar ATPase assembly protein VMA12 (VMA12) is a protein from Homo sapiens identified by UniProt accession Q8N511, 208 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

Target properties

Protein nameVacuolar ATPase assembly protein VMA12
UniProt accessionQ8N511
GeneVMA12
OrganismHomo sapiens
Length208 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N511-F1alphafoldPREDICTED80.37—

Amino-acid sequence (208 residues)

MASSLLAGER LVRALGPGGE LEPERLPRKL RAELEAALGK KHKGGDSSSG PQRLVSFRLI RDLHQHLRER DSKLYLHELL EGSEIYLPEV VKPPRNPELV ARLEKIKIQL ANEEYKRITR NVTCQDTRHG GTLSDLGKQV RSLKALVITI FNFIVTVVAA FVCTYLGSQY IFTEMASRVL AALIVASVVG LAELYVMVRA MEGELGEL

Explore Vacuolar ATPase assembly protein VMA12 with MolForge

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Quick facts

UniProtQ8N511
GeneVMA12
OrganismHomo sapiens
Length208
Binders0
Diseases80
View on UniProt