About Zinc finger protein 276
Zinc finger protein 276 (ZNF276) is a protein
from Homo sapiens identified by UniProt accession
Q8N554, 614 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Zinc finger protein 276 |
|---|
| UniProt accession | Q8N554 |
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| Gene | ZNF276 |
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| Organism | Homo sapiens |
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| Length | 614 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- Fanconi anemia · score 0.57
- Fanconi anemia complementation group A · score 0.57
- ovarian cancer · score 0.27
- platelet component distribution width · score 0.26
- keratinocyte carcinoma · score 0.25
- cystatin C measurement · score 0.24
- mean corpuscular volume · score 0.24
- urate measurement · score 0.23
- intraocular pressure measurement · score 0.21
- mean corpuscular hemoglobin concentration · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N554-F1 | alphafold | PREDICTED | 54.96 | — |
Amino-acid sequence (614 residues)
MKRDRLGRFL SPGSSRQCGA SDGGGGVSRT RGRPSLSGGP RVDGATARRA WGPVGSCGDA GEDGADEAGA GRALAMGHCR LCHGKFSSRS LRSISERAPG ASMERPSAEE RVLVRDFQRL LGVAVRQDPT LSPFVCKSCH AQFYQCHSLL KSFLQRVNAS PAGRRKPCAK VGAQPPTGAE EGACLVDLIT SSPQCLHGLV GWVHGHAASC GALPHLQRTL SSEYCGVIQV VWGCDQGHDY TMDTSSSCKA FLLDSALAVK WPWDKETAPR LPQHRGWNPG DAPQTSQGRG TGTPVGAETK TLPSTDVAQP PSDSDAVGPR SGFPPQPSLP LCRAPGQLGE KQLPSSTSDD RVKDEFSDLS EGDVLSEDEN DKKQNAQSSD ESFEPYPERK VSGKKSESKE AKKSEEPRIR KKPGPKPGWK KKLRCEREEL PTIYKCPYQG CTAVYRGADG MKKHIKEHHE EVRERPCPHP GCNKVFMIDR YLQRHVKLIH TEVRNYICDE CGQTFKQRKH LLVHQMRHSG AKPLQCEVCG FQCRQRASLK YHMTKHKAET ELDFACDQCG RRFEKAHNLN VHMSMVHPLT QTQDKALPLE AEPPPGPPSP SVTTEGQAVK PEPT
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