Melanoregulin (MREG)

Homo sapiens — UniProt Q8N565

Gene: MREGHomo sapiensSwissProt reviewed

About Melanoregulin

Melanoregulin (MREG) is a protein from Homo sapiens identified by UniProt accession Q8N565, 214 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein nameMelanoregulin
UniProt accessionQ8N565
GeneMREG
OrganismHomo sapiens
Length214 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N565-F1alphafoldPREDICTED71.92—

Amino-acid sequence (214 residues)

MGLRDWLRTV CCCCGCECLE ERALPEKEPL VSDNNPYSSF GATLVRDDEK NLWSMPHDVS HTEADDDRTL YNLIVIRNQQ AKDSEEWQKL NYDIHTLRQV RREVRNRWKC ILEDLGFQKE ADSLLSVTKL STISDSKNTR KAREMLLKLA EETNIFPTSW ELSERYLFVV DRLIALDAAE EFFKLARRTY PKKPGVPCLA DGQKELHYLP FPSP

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Quick facts

UniProtQ8N565
GeneMREG
OrganismHomo sapiens
Length214
Binders0
Diseases49
View on UniProt