About Zinc finger protein 561
Zinc finger protein 561 (ZNF561) is a protein
from Homo sapiens identified by UniProt accession
Q8N587, 486 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 561 |
|---|
| UniProt accession | Q8N587 |
|---|
| Gene | ZNF561 |
|---|
| Organism | Homo sapiens |
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| Length | 486 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.04
- appendicular lean mass · score 0.02
- hypertrophic cardiomyopathy · score 0.02
- myocardial infarction · score 0.02
- hepatocellular carcinoma · score 0.01
- laryngeal squamous cell carcinoma · score 0.00
- Uveal melanoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N587-F1 | alphafold | PREDICTED | 60.16 | — |
Amino-acid sequence (486 residues)
MAAIYLSRGF FSREPICPFE EKTKVERMVE DYLASGYQDS VTFDDVAVDF TPEEWALLDT TEKYLYRDVM LENYMNLASV EWEIQPRTKR SSLQQGFLKN QIFSGIQMTR GYSGWKLCDC KNCGEVFREQ FCLKTHMRVQ NGGNTSEGNC YGKDTLSVHK EASTGQELSK FNPCGKVFTL TPGLAVHLEV LNARQPYKCK ECGKGFKYFA SLDNHMGIHT DEKLCEFQEY GRAVTASSHL KQCVAVHTGK KSKKTKKCGK SFTNFSQLYA PVKTHKGEKS FECKECGRSF RNSSCLNDHI QIHTGIKPHK CTYCGKAFTR STQLTEHVRT HTGIKPYECK ECGQAFAQYS GLSIHIRSHS GKKPYQCKEC GKAFTTSTSL IQHTRIHTGE KPYECVECGK TFITSSRRSK HLKTHSGEKP FVCKICGKAF LYSSRLNVHL RTHTGEKPFV CKECGKAFAV SSRLSRHERI HTGEKPYECK DMSVTI
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