Transmembrane protein 156 (TMEM156)

About Transmembrane protein 156

Transmembrane protein 156 (TMEM156) is a protein from Homo sapiens identified by UniProt accession Q8N614, 296 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Transmembrane protein 156
UniProt accession	Q8N614
Gene	TMEM156
Organism	Homo sapiens
Length	296 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

monocyte count · score 0.44
eosinophil count · score 0.40
bone density · score 0.39
urate measurement · score 0.39
mean corpuscular hemoglobin · score 0.35
monocyte percentage of leukocytes · score 0.33
eosinophil percentage of leukocytes · score 0.25
mean corpuscular volume · score 0.23
mean corpuscular hemoglobin concentration · score 0.17
red blood cell density measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N614-F1	alphafold	PREDICTED	43.05	—

Amino-acid sequence (296 residues)

MTKTALLKLF VAIVITFILI LPEYFKTPKE RTLELSCLEV CLQSNFTYSL SSLNFSFVTF LQPVRETQII MRIFLNPSNF RNFTRTCQDI TGEFKMCSSC LVCESKGNMD FISQEQTSKV LIRRGSMEVK ANDFHSPCQH FNFSVAPLVD HLEEYNTTCH LKNHTGRSTI MEDEPSKEKS INYTCRIMEY PNDCIHISLH LEMDIKNITC SMKITWYILV LLVFIFLIIL TIRKILEGQR RVQKWQSHRD KPTSVLLRGS DSEKLRALNV QVLSAETTQR LPLDQVQEVL PPIPEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards