About Olfactory receptor 2C3
Olfactory receptor 2C3 (OR2C3) is a protein
from Homo sapiens identified by UniProt accession
Q8N628, 320 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Olfactory receptor 2C3 |
|---|
| UniProt accession | Q8N628 |
|---|
| Gene | OR2C3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 320 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- mean platelet volume · score 0.14
- platelet count · score 0.11
- platelet component distribution width · score 0.10
- platelet crit · score 0.10
- reticulocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N628-F1 | alphafold | PREDICTED | 86.65 | — |
Amino-acid sequence (320 residues)
MMEIANVSSP EVFVLLGFST RPSLETVLFI VVLSFYMVSI LGNGIIILVS HTDVHLHTPM YFFLANLPFL DMSFTTSIVP QLLANLWGPQ KTISYGGCVV QFYISHWLGA TECVLLATMS YDRYAAICRP LHYTVIMHPQ LCLGLALASW LGGLTTSMVG STLTMLLPLC GNNCIDHFFC EMPLIMQLAC VDTSLNEMEM YLASFVFVVL PLGLILVSYG HIARAVLKIR SAEGRRKAFN TCSSHVAVVS LFYGSIIFMY LQPAKSTSHE QGKFIALFYT VVTPALNPLI YTLRNTEVKS ALRHMVLENC CGSAGKLAQI
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