DNA damage-regulated autophagy modulator protein 1 (DRAM1)

About DNA damage-regulated autophagy modulator protein 1

DNA damage-regulated autophagy modulator protein 1 (DRAM1) is a protein from Homo sapiens identified by UniProt accession Q8N682, 238 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.

Target properties

Protein name	DNA damage-regulated autophagy modulator protein 1
UniProt accession	Q8N682
Gene	DRAM1
Organism	Homo sapiens
Length	238 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N682-F1	alphafold	PREDICTED	94.85	—

Amino-acid sequence (238 residues)

MLCFLRGMAF VPFLLVTWSS AAFIISYVVA VLSGHVNPFL PYISDTGTTP PESGIFGFMI NFSAFLGAAT MYTRYKIVQK QNQTCYFSTP VFNLVSLVLG LVGCFGMGIV ANFQELAVPV VHDGGALLAF VCGVVYTLLQ SIISYKSCPQ WNSLSTCHIR MVISAVSCAA VIPMIVCASL ISITKLEWNP REKDYVYHVV SAICEWTVAF GFIFYFLTFI QDFQSVTLRI STEINGDI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards