About Zinc finger protein 655
Zinc finger protein 655 (ZNF655) is a protein
from Homo sapiens identified by UniProt accession
Q8N720, 491 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Zinc finger protein 655 |
| UniProt accession | Q8N720 |
| Gene | ZNF655 |
| Organism | Homo sapiens |
| Length | 491 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- dehydroepiandrosterone sulphate measurement · score 0.16
- blood metabolite measurement · score 0.13
- myeloid white cell count · score 0.11
- body fat percentage · score 0.09
- platelet count · score 0.09
- body mass index · score 0.08
- age at first sexual intercourse measurement · score 0.08
- lean body mass · score 0.08
- pancreatic neoplasm · score 0.07
- fat body mass · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8N720-F1 | alphafold | PREDICTED | 53.81 | — |
Amino-acid sequence (491 residues)
MEEIPAQEAA GSPRVQFQSL ETQSECLSPE PQFVQDTDME QGLTGDGETR EENKLLIPKQ KISEEVHSYK VRVGRLKHDI TQVPETREVY KSEDRLERLQ EILRKFLYLE REFRQITISK ETFTSEKNNE CHEPEKSFSL DSTIDADQRV LRIQNTDDND KYDMSFNQNS ASGKHEHLNL TEDFQSSECK ESLMDLSHLN KWESIPNTEK SYKCDVCGKI FHQSSALTRH QRIHTREKPY KCKECEKSFS QSSSLSRHKR IHTREKPYKC EASDKSCEAS DKSCSPSSGI IQHKKIHTRA KSYKCSSCER VFSRSVHLTQ HQKIHKEMPC KCTVCGSDFC HTSYLLEHQR VHHEEKAYEY DEYGLAYIKQ QGIHFREKPY TCSECGKDFR LNSHLIQHQR IHTGEKAHEC NECGKAFSQT SCLIQHHKMH RKEKSYECNE YEGSFSHSSD LILQQEVLTR QKAFDCDVWE KNSSQRAHLV QHQSIHTKEN S
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