About Neuropeptide W
Neuropeptide W (NPW) is a protein
from Homo sapiens identified by UniProt accession
Q8N729, 165 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Neuropeptide W |
|---|
| UniProt accession | Q8N729 |
|---|
| Gene | NPW |
|---|
| Organism | Homo sapiens |
|---|
| Length | 165 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- blood protein measurement · score 0.31
- systolic blood pressure · score 0.24
- diastolic blood pressure · score 0.20
- body fat percentage · score 0.09
- Red cell distribution width · score 0.08
- type 1 diabetes mellitus · score 0.04
- hypertension · score 0.03
- non-small cell lung carcinoma · score 0.02
- hepatocellular carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N729-F1 | alphafold | PREDICTED | 58.28 | — |
Amino-acid sequence (165 residues)
MAWRPGERGA PASRPRLALL LLLLLLPLPS GAWYKHVASP RYHTVGRAAG LLMGLRRSPY LWRRALRAAA GPLARDTLSP EPAAREAPLL LPSWVQELWE TRRRSSQAGI PVRAPRSPRA PEPALEPESL DFSGAGQRLR RDVSRPAVDP AANRLGLPCL APGPF
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