About Solute carrier family 66 member 3
Solute carrier family 66 member 3 (SLC66A3) is a protein
from Homo sapiens identified by UniProt accession
Q8N755, 202 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Solute carrier family 66 member 3 |
|---|
| UniProt accession | Q8N755 |
|---|
| Gene | SLC66A3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 202 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.20
- lymphocyte count · score 0.20
- BMI-adjusted waist-hip ratio · score 0.17
- mean reticulocyte volume · score 0.16
- uterine fibroid · score 0.14
- platelet component distribution width · score 0.14
- waist-hip ratio · score 0.12
- mathematical ability · score 0.11
- body fat percentage · score 0.09
- body height · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N755-F1 | alphafold | PREDICTED | 91.77 | — |
Amino-acid sequence (202 residues)
MEAALLGLCN WSTLGVCAAL KLPQISAVLA ARSARGLSLP SLLLELAGFL VFLRYQCYYG YPPLTYLEYP ILIAQDVILL LCIFHFNGNV KQATPYIAVL VSSWFILALQ KWIIDLAMNL CTFISAASKF AQLQCLWKTR DSGTVSALTW SLSSYTCATR IITTLMTTND FTILLRFVIM LALNIWVTVT VLRYRKTAIK AE
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