About Claudin-22
Claudin-22 (CLDN22) is a protein
from Homo sapiens identified by UniProt accession
Q8N7P3, 220 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Claudin-22 |
|---|
| UniProt accession | Q8N7P3 |
|---|
| Gene | CLDN22 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.15
- body height · score 0.08
- heel bone mineral density · score 0.08
- serum gamma-glutamyl transferase measurement · score 0.08
- appendicular lean mass · score 0.07
- mean platelet volume · score 0.07
- FEV/FVC ratio · score 0.06
- HbA1c measurement · score 0.06
- red blood cell density measurement · score 0.06
- vital capacity · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N7P3-F1 | alphafold | PREDICTED | 86.56 | — |
Amino-acid sequence (220 residues)
MALVFRTVAQ LAGVSLSLLG WVLSCLTNYL PHWKNLNLDL NEMENWTMGL WQTCVIQEEV GMQCKDFDSF LALPAELRVS RILMFLSNGL GFLGLLVSGF GLDCLRIGES QRDLKRRLLI LGGILSWASG VTALVPVSWV AHKTVQEFWD ENVPDFVPRW EFGEALFLGW FAGLSLLLGG CLLHCAACSS HAPLASGHYA VAQTQDHHQE LETRNTNLKH
Explore Claudin-22 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets