About Zinc finger protein 366
Zinc finger protein 366 (ZNF366) is a protein
from Homo sapiens identified by UniProt accession
Q8N895, 744 residues long.
MolForge cross-references it against 0 known binders and
141 disease associations.
Target properties
| Protein name | Zinc finger protein 366 |
|---|
| UniProt accession | Q8N895 |
|---|
| Gene | ZNF366 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 744 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (141)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.51
- neutrophil count · score 0.51
- leukocyte count · score 0.49
- alkaline phosphatase measurement · score 0.45
- myeloid white cell count · score 0.45
- lymphocyte percentage of leukocytes · score 0.45
- neutrophil percentage of leukocytes · score 0.41
- asthma · score 0.40
- intraocular pressure measurement · score 0.40
- BMI-adjusted waist circumference · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N895-F1 | alphafold | PREDICTED | 57.15 | — |
Amino-acid sequence (744 residues)
MQKEMKMIKD EDVHFDLAVK KTPSFPHCLQ PVASRGKAPQ RHPFPEALRG PFSQFRYEPP PGDLDGFPGV FEGAGSRKRK SMPTKMPYNH PAEEVTLALH SEENKNHGLP NLPLLFPQPP RPKYDSQMID LCNVGFQFYR SLEHFGGKPV KQEPIKPSAV WPQPTPTPFL PTPYPYYPKV HPGLMFPFFV PSSSPFPFSR HTFLPKQPPE PLLPRKAEPQ ESEETKQKVE RVDVNVQIDD SYYVDVGGSQ KRWQCPTCEK SYTSKYNLVT HILGHSGIKP HACTHCGKLF KQLSHLHTHM LTHQGTRPHK CQVCHKAFTQ TSHLKRHMMQ HSEVKPHNCR VCGRGFAYPS ELKAHEAKHA SGRENICVEC GLDFPTLAQL KRHLTTHRGP IQYNCSECDK TFQYPSQLQN HMMKHKDIRP YICSECGMEF VQPHHLKQHS LTHKGVKEHK CGICGREFTL LANMKRHVLI HTNIRAYQCH LCYKSFVQKQ TLKAHMIVHS DVKPFKCKLC GKEFNRMHNL MGHMHLHSDS KPFKCLYCPS KFTLKGNLTR HMKVKHGVME RGLHSQGLGR GRIALAQTAG VLRSLEQEEP FDLSQKRRAK VPVFQSDGES AQGSHCHEEE EEDNCYEVEP YSPGLAPQSQ QLCTPEDLST KSEHAPEVLE EACKEEKEDA SKGEWEKRSK GDLGAEGGQE RDCAGRDECL SLRAFQSTRR GPSFSDYLYF KHRDESLKEL LERKMEKQAV LLGI
Explore Zinc finger protein 366 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets