About DAN domain family member 5
DAN domain family member 5 (DAND5) is a protein
from Homo sapiens identified by UniProt accession
Q8N907, 189 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | DAN domain family member 5 |
|---|
| UniProt accession | Q8N907 |
|---|
| Gene | DAND5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 189 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- Heterotaxy · score 0.29
- mean corpuscular volume · score 0.18
- erythrocyte count · score 0.13
- mean corpuscular hemoglobin · score 0.13
- breast cancer · score 0.07
- Drugs used in diabetes use measurement · score 0.06
- cortical surface area measurement · score 0.05
- self reported educational attainment · score 0.05
- Heterotaxia · score 0.05
- BMI-adjusted waist-hip ratio · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N907-F1 | alphafold | PREDICTED | 69.28 | — |
Amino-acid sequence (189 residues)
MLLGQLSTLL CLLSGALPTG SGRPEPQSPR PQSWAAANQT WALGPGALPP LVPASALGSW KAFLGLQKAR QLGMGRLQRG QDEVAAVTLP LNPQEVIQGM CKAVPFVQVF SRPGCSAIRL RNHLCFGHCS SLYIPGSDPT PLVLCNSCMP ARKRWAPVVL WCLTGSSASR RRVKISTMLI EGCHCSPKA
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