Coiled-coil domain-containing protein 89 (CCDC89)

About Coiled-coil domain-containing protein 89

Coiled-coil domain-containing protein 89 (CCDC89) is a protein from Homo sapiens identified by UniProt accession Q8N998, 374 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 89
UniProt accession	Q8N998
Gene	CCDC89
Organism	Homo sapiens
Length	374 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

body height · score 0.07
body fat percentage · score 0.04
mean corpuscular volume · score 0.03
gut microbiome measurement · score 0.03
PHF-tau measurement · score 0.03
neurofibrillary tangles measurement · score 0.03
fat body mass · score 0.03
serum albumin measurement · score 0.03
mathematical ability · score 0.02
gastric carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N998-F1	alphafold	PREDICTED	83.07	—

Amino-acid sequence (374 residues)

MRAPMLQKQQ APRMDTPPPE ERLEKQNEKL NNQEEETEFK ELDGLREALA NLRGLSEEER SEKAMLRSRI EEQSQLICIL KRRSDEALER CQILELLNAE LEEKMMQEAE KLKAQGEYSR KLEERFMTLA ANHELMLRFK DEYKSENIKL REENEKLRLE NSSLFSQALK DEEAKVLQLT VRCEALTGEL ETLKERCAQD ACQAQAREKE LLELQSQQAC THTKETEQLR SQLQTLKQQH QQAVEQIAKA EETHSSLSQE LQARLQTVTR EKEELLQLSI ERGKVLQNKQ AEICQLEEKL EIANEDRKHA LERFEQEAVA VDSNLRVREL QRKVDGIQKA YDELRLQSEA FKKHSLDLLS KERELNGKLR HLSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards