About Coiled-coil domain-containing protein 71L
Coiled-coil domain-containing protein 71L (CCDC71L) is a protein
from Homo sapiens identified by UniProt accession
Q8N9Z2, 235 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 71L |
|---|
| UniProt accession | Q8N9Z2 |
|---|
| Gene | CCDC71L |
|---|
| Organism | Homo sapiens |
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| Length | 235 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (72)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- mean platelet volume · score 0.43
- platelet count · score 0.43
- pulse pressure measurement · score 0.41
- systolic blood pressure · score 0.40
- neutrophil count · score 0.39
- hypertension · score 0.39
- platelet component distribution width · score 0.38
- leukocyte count · score 0.38
- blood protein measurement · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8N9Z2-F1 | alphafold | PREDICTED | 59.96 | — |
Amino-acid sequence (235 residues)
MRRSMKRRRR RRPVAPATAA RGGDFRAEDG AGLEAREEKV VYSRSQLSLA DSTKALGDAF KLFMPRSTEF MSSDAELWSF LCSLKHQFSP HILRSKDVYG YSSCRALVPD PPGPPTARGQ ARRPVPRAAA RRRRRGARAA AARRRKPRPP PPPPPPPEES CPAKPVAPGP CFGGRTLEEI WRAATPTLTT FPTIRVGSDV WGERSLAAAR RRARQVLRVN LEPMVRLRRF PVPRA
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