About Fibrous sheath-interacting protein 1
Fibrous sheath-interacting protein 1 (FSIP1) is a protein
from Homo sapiens identified by UniProt accession
Q8NA03, 581 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | Fibrous sheath-interacting protein 1 |
|---|
| UniProt accession | Q8NA03 |
|---|
| Gene | FSIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 581 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (131)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.46
- serum gamma-glutamyl transferase measurement · score 0.40
- cortical surface area measurement · score 0.30
- uric acid measurement · score 0.30
- vital capacity · score 0.26
- serum alanine aminotransferase measurement · score 0.25
- urinary bladder carcinoma · score 0.09
- neoplasm · score 0.09
- azoospermia · score 0.09
- brain volume measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NA03-F1 | alphafold | PREDICTED | 60.48 | — |
Amino-acid sequence (581 residues)
MDIIKGNLDG ISKPASNSRI RPGSRSSNAS LEVLSTEPGS FKVDTASNLN SGKEDHSESS NTENRRTSND DKQESCSEKI KLAEEGSDED LDLVQHQIIS ECSDEPKLKE LDSQLQDAIQ KMKKLDKILA KKQRREKEIK KQGLEMRIKL WEEIKSAKYS EAWQSKEEME NTKKFLSLTA VSEETVGPSH EEEDTFSSVF HTQIPPEEYE MQMQKLNKDF TCDVERNESL IKSGKKPFSN TEKIELRGKH NQDFIKRNIE LAKESRNPVV MVDREKKRLV ELLKDLDEKD SGLSSSEGDQ SGWVVPVKGY ELAVTQHQQL AEIDIKLQEL SAASPTISSF SPRLENRNNQ KPDRDGERNM EVTPGEKILR NTKEQRDLHN RLREIDEKLK MMKENVLEST SCLSEEQLKC LLDECILKQK SIIKLSSERK KEDIEDVTPV FPQLSRSIIS KLLNESETKV QKTEVEDADM LESEECEASK GYYLTKALTG HNMSEALVTE AENMKCLQFS KDVIISDTKD YFMSKTLGIG RLKRPSFLDD PLYGISVSLS SEDQHLKLSS PENTIADEQE TKDAAEECKE P
Explore Fibrous sheath-interacting protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets