WD repeat-containing protein 31 (WDR31)

About WD repeat-containing protein 31

WD repeat-containing protein 31 (WDR31) is a protein from Homo sapiens identified by UniProt accession Q8NA23, 367 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	WD repeat-containing protein 31
UniProt accession	Q8NA23
Gene	WDR31
Organism	Homo sapiens
Length	367 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

body fat percentage · score 0.21
leukocyte count · score 0.15
neutrophil count · score 0.15
appendicular lean mass · score 0.07
blood protein measurement · score 0.04
sum of basophil and neutrophil counts · score 0.02
neutrophil percentage of leukocytes · score 0.02
monocyte percentage of leukocytes · score 0.02
myeloid white cell count · score 0.02
ciliopathy · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NA23-F1	alphafold	PREDICTED	85.97	—

Amino-acid sequence (367 residues)

MLLLRCQLKQ APPQKVSFRF CVVMGKQQSK LKHSTYKYGR PDEIIEERIQ TKAFQEYSPA HMDTVSVVAA LNSDLCVSGG KDKTVVAYNW KTGNVVKRFK GHEHEITKVA CIPKSSQFFS ASRDRMVMMW DLHGSSQPRQ QLCGHAMVVT GLAVSPDSSQ LCTGSRDNTL LLWDVVTGQS VERASVSRNV VTHLCWVPRE PYILQTSEDK TLRLWDSRGL QVAHMFPAKQ HIQTYCEVSV DGHKCISCSN GFGGEGCEAT LWDLRQTRNR ICEYKGHFQT VASCVFLPRA LALMPLIATS SHDCKVKIWN QDTGACLFTL SLDGSGPLTS LAVGDAISLL CASFNRGIHL LRMDHSQGLE LQEVAAF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards