Zinc finger protein 383 (ZNF383)

About Zinc finger protein 383

Zinc finger protein 383 (ZNF383) is a protein from Homo sapiens identified by UniProt accession Q8NA42, 475 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Zinc finger protein 383
UniProt accession	Q8NA42
Gene	ZNF383
Organism	Homo sapiens
Length	475 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

BMI-adjusted waist circumference · score 0.05
hematocrit · score 0.04
BMI-adjusted waist-hip ratio · score 0.04
smoking status measurement · score 0.04
grip strength measurement · score 0.03
hemoglobin measurement · score 0.03
body height · score 0.03
insomnia · score 0.02
eosinophil count · score 0.02
erythrocyte count · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NA42-F1	alphafold	PREDICTED	73.53	—

Amino-acid sequence (475 residues)

MAEGSVMFSD VSIDFSQEEW DCLDPVQRDL YRDVMLENYG NLVSMGLYTP KPQVISLLEQ GKEPWMVGRE LTRGLCSDLE SMCETKLLSL KKEVYEIELC QREIMGLTKH GLEYSSFGDV LEYRSHLAKQ LGYPNGHFSQ EIFTPEYMPT FIQQTFLTLH QIINNEDRPY ECKKCGKAFS QNSQFIQHQR IHIGEKSYEC KECGKFFSCG SHVTRHLKIH TGEKPFECKE CGKAFSCSSY LSQHQRIHTG KKPYECKECG KAFSYCSNLI DHQRIHTGEK PYECKVCGKA FTKSSQLFQH ARIHTGEKPY ECKECGKAFT QSSKLVQHQR IHTGEKPYEC KECGKAFSSG SALTNHQRIH TGEKPYDCKE CGKAFTQSSQ LRQHQRIHAG EKPFECLECG KAFTQNSQLF QHQRIHTDEK PYECNECGKA FNKCSNLTRH LRIHTGEKPY NCKECGKAFS SGSDLIRHQG IHTNK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards