About Coiled-coil domain-containing protein 63
Coiled-coil domain-containing protein 63 (CCDC63) is a protein
from Homo sapiens identified by UniProt accession
Q8NA47, 563 residues long.
MolForge cross-references it against 0 known binders and
112 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 63 |
|---|
| UniProt accession | Q8NA47 |
|---|
| Gene | CCDC63 |
|---|
| Organism | Homo sapiens |
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| Length | 563 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (112)
Diseases linked to this target (Open Targets).
- platelet count · score 0.37
- hemoglobin measurement · score 0.30
- neutrophil count · score 0.30
- eosinophil count · score 0.25
- diastolic blood pressure · score 0.22
- alcohol drinking · score 0.22
- alcohol consumption measurement · score 0.18
- metabolic syndrome · score 0.18
- coronary artery disease · score 0.14
- drinking behavior · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NA47-F1 | alphafold | PREDICTED | 78.38 | — |
Amino-acid sequence (563 residues)
MSVLKKNRRK DSDTPQEPSE KAKEQQAEAE LRKLRQQFRK MVESRKSFKF RNQQKIASQY KEIKTLKTEQ DEITLLLSLM KSSRNMNRSE KNYMELRLLL QTKEDYEALI KSLKVLLAEL DEKILQMEKK IANQKQIFAK MQEANNPRKL QKQIHILETR LNLVTVHFDK MLTTNAKLRK EIEDLRFEKA AYDNVYQQLQ HCLLMEKKTM NLAIEQSSQA YEQRVEAMAR MAAMKDRQKK DTSQYNLEIR ELERLYAHES KLKSFLLVKL NDRNEFEEQA KREEALKAKK HVKKNRGESF ESYEVAHLRL LKLAESGNLN QLIEDFLAKE EKNFARFTYV TELNNDMEMM HKRTQRIQDE IILLRSQQKL SHDDNHSVLR QLEDKLRKTT EEADMYESKY GEVSKTLDLL KNSVEKLFKK INCDATKILV QLGETGKVTD INLPQYFAII EKKTNDLLLL ETYRRILEVE GAEAEIPPPF INPFWGGSAL LKPPEPIKVI PPVLGADPFS DRLDDVEQPL DHSSLRQLVL DNYILKENRS KEVRGDSLPE KVDDFRSRKK VTM
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