Stabilizer of axonemal microtubules 5 (SAXO5)

About Stabilizer of axonemal microtubules 5

Stabilizer of axonemal microtubules 5 (SAXO5) is a protein from Homo sapiens identified by UniProt accession Q8NA69, 505 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Stabilizer of axonemal microtubules 5
UniProt accession	Q8NA69
Gene	SAXO5
Organism	Homo sapiens
Length	505 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

cystatin C measurement · score 0.06
serum urea measurement · score 0.05
hypertension · score 0.04
hair colour measurement · score 0.04
cardiovascular disease · score 0.04
blood protein measurement · score 0.04
electrocardiography · score 0.04
systolic blood pressure · score 0.04
diastolic blood pressure · score 0.03
sitting height measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NA69-F1	alphafold	PREDICTED	54.24	—

Amino-acid sequence (505 residues)

MATGALLPCS RPCPMSRLDF LKASHFSLGP DLRLHEGTMR TTSHRDFAYP AATREPPSLQ PPPALLFPMD PRWDREERVS EAHRAFPPPS TPPWELLQAQ ARERTLAMQA GNLHLHEDAH AGIGLSNAHA AYGWPELPAR TRERIRGARL IFDRDSLPPG DRDKLRIPPT THQALFPPHD ARPQPRAPSC HLGGPNTLKW DYTRQDGTSY QRQFQALPGP PALRCKRASS GVELGDCKIS YGSTCSEQKQ AYRPQDLPED RYDKAQATAH IHCVNIRPGD GLFRDRTTKA EHFYAREPEP FVLHHDQTPE SHILKGNWCP GPGSLDTFMQ YFYGQPPPPT QPPSRHVPHE KLQSHVTLGE PKLLKRFFKT TMGSDYCPSE WRQVQKAPNL HLQQSYLPRG TGEFDFLTMN QKMLKPHRTP PAPVTEEMLQ RCKYSHMEPP LGGLRFFSTQ YKDEFPFKYQ GPAALRLKNP QEGFVPLGTP HQRGCREKID PLVPQPPMYL CPSQQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards