About Protein Atg16l2
Protein Atg16l2 (ATG16L2) is a protein
from Homo sapiens identified by UniProt accession
Q8NAA4, 619 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Protein Atg16l2 |
|---|
| UniProt accession | Q8NAA4 |
|---|
| Gene | ATG16L2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 619 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- serum non-albumin protein measurement · score 0.28
- coronary artery disease · score 0.25
- systemic lupus erythematosus · score 0.22
- aspartate aminotransferase measurement · score 0.20
- Crohn's disease · score 0.15
- genetic disorder · score 0.12
- mean platelet volume · score 0.10
- platelet count · score 0.08
- mean corpuscular volume · score 0.07
- serum alanine aminotransferase measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NAA4-F1 | alphafold | PREDICTED | 80.57 | — |
Amino-acid sequence (619 residues)
MAGPGVPGAP AARWKRHIVR QLRLRDRTQK ALFLELVPAY NHLLEKAELL DKFSKKLQPE PNSVTPTTHQ GPWEESELDS DQVPSLVALR VKWQEEEEGL RLVCGEMAYQ VVEKGAALGT LESELQQRQS RLAALEARVA QLREARAQQA QQVEEWRAQN AVQRAAYEAL RAHVGLREAA LRRLQEEARD LLERLVQRKA RAAAERNLRN ERRERAKQAR VSQELKKAAK RTVSISEGPD TLGDGMRERR ETLALAPEPE PLEKEACEKW KRPFRSASAT SLTLSHCVDV VKGLLDFKKR RGHSIGGAPE QRYQIIPVCV AARLPTRAQD VLDAHLSEVN AVRFGPNSSL LATGGADRLI HLWNVVGSRL EANQTLEGAG GSITSVDFDP SGYQVLAATY NQAAQLWKVG EAQSKETLSG HKDKVTAAKF KLTRHQAVTG SRDRTVKEWD LGRAYCSRTI NVLSYCNDVV CGDHIIISGH NDQKIRFWDS RGPHCTQVIP VQGRVTSLSL SHDQLHLLSC SRDNTLKVID LRVSNIRQVF RADGFKCGSD WTKAVFSPDR SYALAGSCDG ALYIWDVDTG KLESRLQGPH CAAVNAVAWC YSGSHMVSVD QGRKVVLWQ
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