About Zinc finger and BTB domain-containing protein 8B
Zinc finger and BTB domain-containing protein 8B (ZBTB8B) is a protein
from Homo sapiens identified by UniProt accession
Q8NAP8, 495 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 8B |
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| UniProt accession | Q8NAP8 |
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| Gene | ZBTB8B |
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| Organism | Homo sapiens |
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| Length | 495 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (3)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.04
- cancer · score 0.01
- uterine leiomyosarcoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NAP8-F1 | alphafold | PREDICTED | 57.98 | — |
Amino-acid sequence (495 residues)
MEMQSYYAKL LGELNEQRKR DFFCDCSIIV EGRIFKAHRN ILFANSGYFR ALLIHYIQDS GRHSTASLDI VTSDAFSIIL DFLYSGKLDL CGENVIEVMS AASYLQMNDV VNFCKTYIRS SLDICRKMEK EAAVAAAVAA AAAAAAAAAA AAAHQVDSES PSSGREGTSC GTKSLVSSPA EGEKSVECLR ESPCGDCGDC HPLELVVRDS LGGGSADSNL STPPKRIEPK VEFDADEVEV DVGEQLQQYA APLNLAHVEE ALPSGQAVDL AYSNYHVKQF LEALLRNSAA PSKDDADHHF SRSLEGRPEG AGVAMSSMMD VQADWYGEDS GDVLVVPIKL HKCPFCPYTA KQKGILKRHI RSHTGERPYP CETCGKRFTR QEHLRSHALS VHRSNRPIIC KGCRRTFTSH LSQGLRRFGL CDSCTCVTDT PDDDDDLMPI NLSLVEASSE SQEKSDTDND WPIYVESGEE NDPAGDDSDD KPQIQPNLSD RETLT
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