About Tudor domain-containing protein 5
Tudor domain-containing protein 5 (TDRD5) is a protein
from Homo sapiens identified by UniProt accession
Q8NAT2, 981 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Tudor domain-containing protein 5 |
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| UniProt accession | Q8NAT2 |
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| Gene | TDRD5 |
|---|
| Organism | Homo sapiens |
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| Length | 981 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NAT2-F1 | alphafold | PREDICTED | 59.57 | — |
Amino-acid sequence (981 residues)
MSEQERIQEC LRKEIRSLLI STKDGLSPQE LEKEYLLMVG NHLPLRILGY RSTMELVLDM PDVVRVCPGA GGTVILKAIP DESTKGIASL VAKQRSSHKL RNSMHKGRPS IYSGPRSHRR VPYRGRVAPI LPAVVKSELK DLLALSPVLL SDFEKAFAKR FGRSFQYMQY GFLSMFEVLN AASDVISVEQ TRAGSLLMLK KSVTEEKPRG CPAGKIFTQP FRMKQGSYST GFPVAKPCFS QPTSNMEPPK QIMSMEKTSK LNVVETSRLN HTEKLNQLEN TFKSVIAQIG PGGTISSELK HKIKFVVSKF PEGLFISKLL GEYEVIFKEQ LSPKKLGFLN VTELVGALSD ILHVEFRKGH QDLLVFDADK KPLPPVQSDK KIEAKACVSS PPRNSLSTAA VKETVWNCPS KKQKEPQQKI CKKPNLVVKP LQLQVETNKS ELNLAMANHD IPPDAVPNKK LCRLPPLDTS SLIGVFVEYI ISPSQFYIRI YSRDSSELLE DMMIEMRRCY SNQLVSDRYV MPECFIQPGH LCCVRISEDK WWYRVIIHRV LEKQEVEVFY PDFGNIGIVQ KSSLRFLKCC YTKLPAQAIP CSLAWVRPVE EHWTSKAILQ FQKLCGLKPL VGVVDEYVDG ILNIFLCDTS SNEDVYFHHV LRTEGHAIVC RENISSKGFS ELNPLALYTT SSGGPEDIVL TELGYPSQQH YFNEDRKISP QSKESELRIL DEIPTGMPCL ESVTIGDDIW DENWLPLQAK MGKGGDAASH LFTASLGGKN QYSSCKEMPQ KDWCFSTPKD TWDDSWQPSG LVNGTKVEVH KPEVLGAQEK NTGTNRTQKQ LDINGSSDSS TLPKLEEFCT SLTQSEQSAD GSQSEPNNSQ TQPKQIQLST AAPCSTTAVD DSAEKPSGSV ESSPEILKNE DFSSSRAITL YKDKRQESVD QLSLILSYEC QISQKLYIPR STATAALGAA ARLATSRSLL HWYPSVKRME A
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