Zinc finger protein 527 (ZNF527)

About Zinc finger protein 527

Zinc finger protein 527 (ZNF527) is a protein from Homo sapiens identified by UniProt accession Q8NB42, 609 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Zinc finger protein 527
UniProt accession	Q8NB42
Gene	ZNF527
Organism	Homo sapiens
Length	609 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

hematocrit · score 0.13
hypertension · score 0.05
sex hormone-binding globulin measurement · score 0.04
hemoglobin measurement · score 0.03
body height · score 0.03
smoking status measurement · score 0.02
erythrocyte count · score 0.02
diastolic blood pressure · score 0.02
Intellectual disability · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NB42-F1	alphafold	PREDICTED	64.10	—

Amino-acid sequence (609 residues)

MAVGLCKAMS QGLVTFRDVA LDFSQEEWEW LKPSQKDLYR DVMLENYRNL VWLGLSISKP NMISLLEQGK EPWMVERKMS QGHCADWESW CEIEELSPKW FIDEDEISQE MVMERLASHG LECSSFREAW KYKGEFELHQ GNAERHFMQV TAVKEISTGK RDNEFSNSGR SIPLKSVFLT QQKVPTIQQV HKFDIYDKLF PQNSVIIEYK RLHAEKESLI GNECEEFNQS TYLSKDIGIP PGEKPYESHD FSKLLSFHSL FTQHQTTHFG KLPHGYDECG DAFSCYSFFT QPQRIHSGEK PYACNDCGKA FSHDFFLSEH QRTHIGEKPY ECKECNKAFR QSAHLAQHQR IHTGEKPFAC NECGKAFSRY AFLVEHQRIH TGEKPYECKE CNKAFRQSAH LNQHQRIHTG EKPYECNQCG KAFSRRIALT LHQRIHTGEK PFKCSECGKT FGYRSHLNQH QRIHTGEKPY ECIKCGKFFR TDSQLNRHHR IHTGERPFEC SKCGKAFSDA LVLIHHKRSH AGEKPYECNK CGKAFSCGSY LNQHQRIHTG EKPYECSECG KAFHQILSLR LHQRIHAGEK PYKCNECGNN FSCVSALRRH QRIHNRETL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards