About Zinc finger protein GLIS1
Zinc finger protein GLIS1 (GLIS1) is a protein
from Homo sapiens identified by UniProt accession
Q8NBF1, 620 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Zinc finger protein GLIS1 |
|---|
| UniProt accession | Q8NBF1 |
|---|
| Gene | GLIS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 620 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (61)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.42
- grip strength measurement · score 0.42
- body height · score 0.41
- hair shape measurement · score 0.39
- digit length ratio · score 0.39
- neurodegenerative disease · score 0.34
- urate measurement · score 0.33
- synophrys measurement · score 0.30
- nose morphology measurement · score 0.30
- Abnormality of refraction · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NBF1-F1 | alphafold | PREDICTED | 52.83 | — |
Amino-acid sequence (620 residues)
MAEARTSLSA HCRGPLATGL HPDLDLPGRS LATPAPSCYL LGSEPSSGLG LQPETHLPEG SLKRCCVLGL PPTSPASSSP CASSDVTSII RSSQTSLVTC VNGLRSPPLT GDLGGPSKRA RPGPASTDSH EGSLQLEACR KASFLKQEPA DEFSELFGPH QQGLPPPYPL SQLPPGPSLG GLGLGLAGRV VAGRQACRWV DCCAAYEQQE ELVRHIEKSH IDQRKGEDFT CFWAGCVRRY KPFNARYKLL IHMRVHSGEK PNKCMFEGCS KAFSRLENLK IHLRSHTGEK PYLCQHPGCQ KAFSNSSDRA KHQRTHLDTK PYACQIPGCS KRYTDPSSLR KHVKAHSAKE QQVRKKLHAG PDTEADVLTE CLVLQQLHTS TQLAASDGKG GCGLGQELLP GVYPGSITPH NGLASGLLPP AHDVPSRHHP LDATTSSHHH LSPLPMAEST RDGLGPGLLS PIVSPLKGLG PPPLPPSSQS HSPGGQPFPT LPSKPSYPPF QSPPPPPLPS PQGYQGSFHS IQSCFPYGDC YRMAEPAAGG DGLVGETHGF NPLRPNGYHS LSTPLPATGY EALAEASCPT ALPQQPSEDV VSSGPEDCGF FPNGAFDHCL GHIPSIYTDT
Explore Zinc finger protein GLIS1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets