Golgi membrane protein 1 (GOLM1)

About Golgi membrane protein 1

Golgi membrane protein 1 (GOLM1) is a protein from Homo sapiens identified by UniProt accession Q8NBJ4, 401 residues long. MolForge cross-references it against 0 known binders and 192 disease associations.

Target properties

Protein name	Golgi membrane protein 1
UniProt accession	Q8NBJ4
Gene	GOLM1
Organism	Homo sapiens
Length	401 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (192)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.31
hepatocellular carcinoma · score 0.12
neoplasm · score 0.10
Cirrhosis · score 0.10
hepatitis C virus infection · score 0.10
non-alcoholic fatty liver disease · score 0.09
non-alcoholic steatohepatitis · score 0.09
cancer · score 0.09
chronic hepatitis B virus infection · score 0.08
head and neck squamous cell carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NBJ4-F1	alphafold	PREDICTED	64.18	—

Amino-acid sequence (401 residues)

MMGLGNGRRS MKSPPLVLAA LVACIIVLGF NYWIASSRSV DLQTRIMELE GRVRRAAAER GAVELKKNEF QGELEKQREQ LDKIQSSHNF QLESVNKLYQ DEKAVLVNNI TTGERLIRVL QDQLKTLQRN YGRLQQDVLQ FQKNQTNLER KFSYDLSQCI NQMKEVKEQC EERIEEVTKK GNEAVASRDL SENNDQRQQL QALSEPQPRL QAAGLPHTEV PQGKGNVLGN SKSQTPAPSS EVVLDSKRQV EKEETNEIQV VNEEPQRDRL PQEPGREQVV EDRPVGGRGF GGAGELGQTP QVQAALSVSQ ENPEMEGPER DQLVIPDGQE EEQEAAGEGR NQQKLRGEDD YNMDENEAES ETDKQAALAG NDRNIDVFNV EDQKRDTINL LDQREKRNHT L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards