Solute carrier family 67 member A2 (SLC67A2)

About Solute carrier family 67 member A2

Solute carrier family 67 member A2 (SLC67A2) is a protein from Homo sapiens identified by UniProt accession Q8NBP5, 474 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Solute carrier family 67 member A2
UniProt accession	Q8NBP5
Gene	SLC67A2
Organism	Homo sapiens
Length	474 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

testosterone measurement · score 0.43
electrocardiography · score 0.18
alcohol consumption measurement · score 0.15
PR interval · score 0.15
self reported educational attainment · score 0.09
eosinophil count · score 0.09
ST2 protein measurement · score 0.07
eosinophilic esophagitis · score 0.06
neurofibrillary tangles measurement · score 0.06
Inhalant adrenergic use measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NBP5-F1	alphafold	PREDICTED	81.06	—

Amino-acid sequence (474 residues)

MELGGHWDMN SAPRLVSETA ERKQEQKTGT EAEAADSGAV GARRFLLCLY LVGFLDLFGV SMVVPLLSLH VKSLGASPTV AGIVGSSYGI LQLFSSTLVG CWSDVVGRRS SLLACILLSA LGYLLLGAAT NVFLFVLARV PAGIFKHTLS ISRALLSDVV PEKERPLVIG HFNTASGVGF ILGPVVGGYL TELEDGFYLT AFICFLVFIL NAGLVWFFPW REAKPGSTEK GLPLRKTHVL LGRSHDTVQE AATSRRARAS KKTAQPWVEV VLALRNMKNL LFSEMWDIFL VRLLMAMAVM LYYSNFVLAL EERFGVRPKV TGYLISYSSM LGAVAGLALG PILRLYKHNS QALLLHSSIL TCTLLLLYSL APTMGAVVLS STLLSFSTAI GRTCITDLQL TVGGAQASGT LIGVGQSVTA VGRIIAPLLS GVAQEVSPCG PPSLGAVLAL VAIFIMSLNK RHSSGDGNSK LKSE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards