About INO80 complex subunit E
INO80 complex subunit E (INO80E) is a protein
from Homo sapiens identified by UniProt accession
Q8NBZ0, 244 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | INO80 complex subunit E |
|---|
| UniProt accession | Q8NBZ0 |
|---|
| Gene | INO80E |
|---|
| Organism | Homo sapiens |
|---|
| Length | 244 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- body mass index · score 0.14
- smoking behavior · score 0.12
- feeling nervous measurement · score 0.11
- emotional symptom measurement · score 0.07
- schizophrenia · score 0.05
- lean body mass · score 0.05
- waist-hip ratio · score 0.05
- body weight · score 0.05
- type 2 diabetes mellitus · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NBZ0-F1 | alphafold | PREDICTED | 65.87 | — |
Amino-acid sequence (244 residues)
MNGPADGEVD YKKKYRNLKR KLKFLIYEHE CFQEELRKAQ RKLLKVSRDK SFLLDRLLQY ENVDEDSSDS DATASSDNSE TEGTPKLSDT PAPKRKRSPP LGGAPSPSSL SLPPSTGFPL QASGVPSPYL SSLASSRYPP FPSDYLALQL PEPSPLRPKR EKRPRLPRKL KMAVGPPDCP VGGPLTFPGR GSGAGVGTTL TPLPPPKMPP PTILSTVPRQ MFSDAGSGDD ALDGDDDLVI DIPE
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