Zinc finger protein 114 (ZNF114)

About Zinc finger protein 114

Zinc finger protein 114 (ZNF114) is a protein from Homo sapiens identified by UniProt accession Q8NC26, 417 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Zinc finger protein 114
UniProt accession	Q8NC26
Gene	ZNF114
Organism	Homo sapiens
Length	417 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

multiple sclerosis · score 0.25
neurodegenerative disease · score 0.25
lysosomal storage disease · score 0.25
Alzheimer disease · score 0.25
Parkinson disease · score 0.25
protein measurement · score 0.21
platelet count · score 0.16
platelet crit · score 0.04
sitting height measurement · score 0.02
lip and oral cavity carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NC26-F1	alphafold	PREDICTED	45.82	—

Amino-acid sequence (417 residues)

MSQDSVTFAD VAVNFTKEEW TLLDPAQRNL YRDVMLENSR NLAFIDWATP CKTKDATPQP DILPKRTFPE ANRVCLTSIS SQHSTLREDW RCPKTEEPHR QGVNNVKPPA VAPEKDESPV SICEDHEMRN HSKPTCRLVP SQGDSIRQCI LTRDSSIFKY NPVLNDSQKT HENNEDDGVL GWNIQWVPCG RKTELKSSTW TGSQNTVHHI RDEIDTGANR HQRNPFGKAF REDGSLRAHN THGREKMYDF TQCENTSRNN SIHAMQMQLY TAETNKKDCQ TGATSANAPN SGSHKSHCTG EKTHKCPECG RAFFYQSFLM RHMKIHTGEK PYECGKCGKA FRYSLHLNKH LRKHVVQKKP YECEECGKVI RESSKYTHIR SHTGEKPYKC KTCGKDFAKS SGLKKHLKTH KDEKPCE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards