CaM kinase-like vesicle-associated protein (CAMKV)

About CaM kinase-like vesicle-associated protein

CaM kinase-like vesicle-associated protein (CAMKV) is a protein from Homo sapiens identified by UniProt accession Q8NCB2, 501 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	CaM kinase-like vesicle-associated protein
UniProt accession	Q8NCB2
Gene	CAMKV
Organism	Homo sapiens
Length	501 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (95)

Diseases linked to this target (Open Targets).

age at first birth measurement · score 0.27
body mass index · score 0.26
body fat percentage · score 0.25
fat body mass · score 0.21
self reported educational attainment · score 0.18
lean body mass · score 0.17
neurodegenerative disease · score 0.17
mean corpuscular volume · score 0.15
lifestyle measurement · score 0.14
body weight · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NCB2-F1	alphafold	PREDICTED	70.65	—

Amino-acid sequence (501 residues)

MPFGCVTLGD KKNYNQPSEV TDRYDLGQVI KTEEFCEIFR AKDKTTGKLH TCKKFQKRDG RKVRKAAKNE IGILKMVKHP NILQLVDVFV TRKEYFIFLE LATGREVFDW ILDQGYYSER DTSNVVRQVL EAVAYLHSLK IVHRNLKLEN LVYYNRLKNS KIVISDFHLA KLENGLIKEP CGTPEYLAPE VVGRQRYGRP VDCWAIGVIM YILLSGNPPF YEEVEEDDYE NHDKNLFRKI LAGDYEFDSP YWDDISQAAK DLVTRLMEVE QDQRITAEEA ISHEWISGNA ASDKNIKDGV CAQIEKNFAR AKWKKAVRVT TLMKRLRAPE QSSTAAAQSA SATDTATPGA AGGATAAAAS GATSAPEGDA ARAAKSDNVA PADRSATPAT DGSATPATDG SVTPATDGSI TPATDGSVTP ATDRSATPAT DGRATPATEE STVPTTQSSA MLATKAAATP EPAMAQPDST APEGATGQAP PSSKGEEAAG YAQESQREEA S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards