About Putative tyrosine carboxypeptidase MATCAP2
Putative tyrosine carboxypeptidase MATCAP2 (MATCAP2) is a protein
from Homo sapiens identified by UniProt accession
Q8NCT3, 520 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Putative tyrosine carboxypeptidase MATCAP2 |
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| UniProt accession | Q8NCT3 |
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| Gene | MATCAP2 |
|---|
| Organism | Homo sapiens |
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| Length | 520 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.41
- Red cell distribution width · score 0.38
- mean corpuscular hemoglobin · score 0.31
- mean reticulocyte volume · score 0.30
- mean corpuscular hemoglobin concentration · score 0.25
- reticulocyte count · score 0.16
- platelet count · score 0.10
- Iron deficiency anemia · score 0.10
- reticulocyte measurement · score 0.09
- high density lipoprotein cholesterol measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NCT3-F1 | alphafold | PREDICTED | 59.23 | — |
Amino-acid sequence (520 residues)
MAGCTRKLTH LRKRIHRPRR RTTRRWKRWF KFRKRKGEKR PRPNHKAVAR RAKLKFSTSE KLHWPEQELA KKSILNAEDS LIIDNKRSIS HLSSGVLKDI FTTGTSSYNV LLQSKEEKKY HSQKQSSSTY SKRCRKPSKS PNTSRSKDPR RMKALVPVTS SGTWYCLERR PAVFVTSSVS SPVKFTHDIS VTGNGIVLPP KPKSKVKWCH FSTLPKPKPQ LSRSFEKGDD FSGKKFCILT AIKPTNLEKE KLRFFKSDYT YNPQFEYANP ALPSVLAKHS HASDRFLKQI VVHLTEDLLS RASMTVVNGC PTLTINVSTA REHWLEGMLR HEIGTHYFRG INNLQQPWNS WTGRKKHELK PNNPTEEGLA SIHSVLFRKD PFLWRAALLY YTVYQASQMS FCELFKDIGR FVKDPNTRWD YCVRAKRGWT DTSQPGCFSK DQVYLDGILQ ILRYRDTIDF HLLTALGKVS YEDVDRLKGL AVTENMRVPH FLQDHGRYME HLEKIMEVNE LTDRELKDLI
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